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Thermodynamics of Damaged DNA Binding and Catalysis by Human AP Endonuclease 1

Apurinic/apyrimidinic (AP) endonucleases play an important role in DNA repair and initiation of AP site elimination. One of the most topical problems in the field of DNA repair is to understand the mechanism of the enzymatic process involving the human enzyme APE1 that provides recognition of AP sit...

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Foilsithe in:Acta Naturae
Main Authors: Miroshnikova, A. D., Kuznetsova, A. A., Kuznetsov, N. A., Fedorova, O. S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: A.I. Gordeyev 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4837577/
https://ncbi.nlm.nih.gov/pubmed/27099790
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