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Cell-Penetrating Pepducin Therapy Targeting PAR1 in Subjects With Coronary Artery Disease
OBJECTIVE: Pepducins are membrane-tethered, cell-penetrating lipopeptides that target the cytoplasmic surface of their cognate receptor. Here, we report the first human use of a protease-activated receptor-1–based pepducin, which is intended as an antiplatelet agent to prevent ischemic complications...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4836853/ https://ncbi.nlm.nih.gov/pubmed/26681756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306777 |
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