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Palladium-Catalyzed Asymmetric Allylic Alkylations with Toluene Derivatives as Pronucleophiles

The first two highly enantioselective palladium-catalyzed allylic alkylations with benzylic nucleophiles activated with Cr(CO)(3) have been developed. These methods enable the enantioselective synthesis of “α-2-propenyl benzyl” motifs, which are important scaffolds in natural products and pharmaceut...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Angew Chem Int Ed Engl
Hauptverfasser: Mao, Jianyou, Zhang, Jiadi, Jiang, Hui, Bellomo, Ana, Zhang, Mengnan, Gao, Zidong, Dreher, Spencer D., Walsh, Patrick J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836847/
https://ncbi.nlm.nih.gov/pubmed/26756125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201509917
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