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Raising the pK(a) Limit of “Soft” Nucleophiles in Palladium-Catalyzed Allylic Substitutions. Application of Diarylmethane Pronucleophiles

The Tsuji-Trost allylic substitution reaction provides a useful and efficient approach to construct C-C bonds between sp(3)-hybridized carbons. The widely accepted paradigm for classifying the mode of attack of nucleophiles on palladium π-allyl intermediates in the Tsuji-Trost reaction is based on t...

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Autores principales: Sha, Sheng-Chun, Zhang, Jiadi, Carroll, Patrick J., Walsh, Patrick J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3896100/
https://ncbi.nlm.nih.gov/pubmed/24147620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja409511n
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