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Unconventional EGF-induced ERK1/2-mediated Kv1.3 endocytosis
The potassium channel Kv1.3 plays roles in immunity, neuronal development and sensory discrimination. Regulation of Kv1.3 by kinase signaling has been studied. In this context, EGF binds to specific receptors (EGFR) and triggers tyrosine kinase-dependent signaling, which down-regulates Kv1.3 current...
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| 出版年: | Cell Mol Life Sci |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Springer International Publishing
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4836834/ https://ncbi.nlm.nih.gov/pubmed/26542799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-015-2082-0 |
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