Unconventional EGF-induced ERK1/2-mediated Kv1.3 endocytosis

The potassium channel Kv1.3 plays roles in immunity, neuronal development and sensory discrimination. Regulation of Kv1.3 by kinase signaling has been studied. In this context, EGF binds to specific receptors (EGFR) and triggers tyrosine kinase-dependent signaling, which down-regulates Kv1.3 current...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Mol Life Sci
Egile Nagusiak: Martínez-Mármol, Ramón, Comes, Núria, Styrczewska, Katarzyna, Pérez-Verdaguer, Mireia, Vicente, Rubén, Pujadas, Lluís, Soriano, Eduardo, Sorkin, Alexander, Felipe, Antonio
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer International Publishing 2015
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836834/
https://ncbi.nlm.nih.gov/pubmed/26542799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-015-2082-0
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