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IFNγ Responses to Pre-erythrocytic and Blood-stage Malaria Antigens Exhibit Differential Associations With Past Exposure and Subsequent Protection

Background. The malaria-specific T-cell response is believed to be important for protective immunity. Antimalarial chemoprevention may affect this response by altering exposure to malaria antigens. Methods. We performed interferon γ (IFNγ) ELISpot assays to assess the cellular immune response to blo...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Jagannathan, Prasanna, Nankya, Felistas, Stoyanov, Cristina, Eccles-James, Ijeoma, Sikyomu, Esther, Naluwu, Kate, Wamala, Samuel, Nalubega, Mayimuna, Briggs, Jessica, Bowen, Katherine, Bigira, Victor, Kapisi, James, Kamya, Moses R., Dorsey, Grant, Feeney, Margaret E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836719/
https://ncbi.nlm.nih.gov/pubmed/25520427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiu814
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