Profilin modulates sarcomeric organization and mediates cardiomyocyte hypertrophy

AIMS: Heart failure is often preceded by cardiac hypertrophy, which is characterized by increased cell size, altered protein abundance, and actin cytoskeletal reorganization. Profilin is a well-conserved, ubiquitously expressed, multifunctional actin-binding protein, and its role in cardiomyocytes i...

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Pubblicato in:Cardiovasc Res
Autori principali: Kooij, Viola, Viswanathan, Meera C., Lee, Dong I., Rainer, Peter P., Schmidt, William, Kronert, William A., Harding, Sian E., Kass, David A., Bernstein, Sanford I., Van Eyk, Jennifer E., Cammarato, Anthony
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836629/
https://ncbi.nlm.nih.gov/pubmed/26956799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvw050
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