Cardiac resynchronization sensitizes the sarcomere to calcium by reactivating GSK-3β

Cardiac resynchronization therapy (CRT), the application of biventricular stimulation to correct discoordinate contraction, is the only heart failure treatment that enhances acute and chronic systolic function, increases cardiac work, and reduces mortality. Resting myocyte function also increases af...

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Detalhes bibliográficos
Main Authors: Kirk, Jonathan A., Holewinski, Ronald J., Kooij, Viola, Agnetti, Giulio, Tunin, Richard S., Witayavanitkul, Namthip, de Tombe, Pieter P., Gao, Wei Dong, Van Eyk, Jennifer, Kass, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871225/
https://ncbi.nlm.nih.gov/pubmed/24292707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69253
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