Cardiac resynchronization sensitizes the sarcomere to calcium by reactivating GSK-3β

Cardiac resynchronization therapy (CRT), the application of biventricular stimulation to correct discoordinate contraction, is the only heart failure treatment that enhances acute and chronic systolic function, increases cardiac work, and reduces mortality. Resting myocyte function also increases af...

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Autori principali: Kirk, Jonathan A., Holewinski, Ronald J., Kooij, Viola, Agnetti, Giulio, Tunin, Richard S., Witayavanitkul, Namthip, de Tombe, Pieter P., Gao, Wei Dong, Van Eyk, Jennifer, Kass, David A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3871225/
https://ncbi.nlm.nih.gov/pubmed/24292707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69253
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