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Small-molecule CFTR activators increase tear secretion and prevent experimental dry eye disease
Dry eye disorders, including Sjögren’s syndrome, constitute a common problem in the aging population, with limited effective therapeutic options available. The cAMP-activated Cl(−) channel cystic fibrosis transmembrane conductance regulator (CFTR) is a major prosecretory channel at the ocular surfac...
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| Publicado no: | FASEB J |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4836376/ https://ncbi.nlm.nih.gov/pubmed/26842854 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201500180 |
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