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Linear Epitopes in Vaccinia Virus A27 Are Targets of Protective Antibodies Induced by Vaccination against Smallpox

Vaccinia virus (VACV) A27 is a target for viral neutralization and part of the Dryvax smallpox vaccine. A27 is one of the three glycosaminoglycan (GAG) adhesion molecules and binds to heparan sulfate. To understand the function of anti-A27 antibodies, especially their protective capacity and their i...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Kaever, Thomas, Matho, Michael H., Meng, Xiangzhi, Crickard, Lindsay, Schlossman, Andrew, Xiang, Yan, Crotty, Shane, Peters, Bjoern, Zajonc, Dirk M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836320/
https://ncbi.nlm.nih.gov/pubmed/26889021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02878-15
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