Linear Epitopes in Vaccinia Virus A27 Are Targets of Protective Antibodies Induced by Vaccination against Smallpox

Vaccinia virus (VACV) A27 is a target for viral neutralization and part of the Dryvax smallpox vaccine. A27 is one of the three glycosaminoglycan (GAG) adhesion molecules and binds to heparan sulfate. To understand the function of anti-A27 antibodies, especially their protective capacity and their i...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Kaever, Thomas, Matho, Michael H., Meng, Xiangzhi, Crickard, Lindsay, Schlossman, Andrew, Xiang, Yan, Crotty, Shane, Peters, Bjoern, Zajonc, Dirk M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836320/
https://ncbi.nlm.nih.gov/pubmed/26889021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02878-15
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