Linear Epitopes in Vaccinia Virus A27 Are Targets of Protective Antibodies Induced by Vaccination against Smallpox

Vaccinia virus (VACV) A27 is a target for viral neutralization and part of the Dryvax smallpox vaccine. A27 is one of the three glycosaminoglycan (GAG) adhesion molecules and binds to heparan sulfate. To understand the function of anti-A27 antibodies, especially their protective capacity and their i...

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Vydáno v:J Virol
Hlavní autoři: Kaever, Thomas, Matho, Michael H., Meng, Xiangzhi, Crickard, Lindsay, Schlossman, Andrew, Xiang, Yan, Crotty, Shane, Peters, Bjoern, Zajonc, Dirk M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836320/
https://ncbi.nlm.nih.gov/pubmed/26889021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02878-15
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