Hypoxia-induced modulation of PTEN activity and EMT phenotypes in lung cancers

BACKGROUND: Persistent hypoxia stimulation, one of the most critical microenvironmental factors, accelerates the acquisition of epithelial–mesenchymal transition (EMT) phenotypes in lung cancer cells. Loss of phosphatase and tensin homologue deleted from chromosome 10 (PTEN) expression might acceler...

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Bibliografiske detaljer
Udgivet i:Cancer Cell Int
Main Authors: Kohnoh, Takashi, Hashimoto, Naozumi, Ando, Akira, Sakamoto, Koji, Miyazaki, Shinichi, Aoyama, Daisuke, Kusunose, Masaaki, Kimura, Motohiro, Omote, Norihito, Imaizumi, Kazuyoshi, Kawabe, Tsutomu, Hasegawa, Yoshinori
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Primary Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836157/
https://ncbi.nlm.nih.gov/pubmed/27095949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-016-0308-3
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