Hypoxia-induced modulation of PTEN activity and EMT phenotypes in lung cancers

BACKGROUND: Persistent hypoxia stimulation, one of the most critical microenvironmental factors, accelerates the acquisition of epithelial–mesenchymal transition (EMT) phenotypes in lung cancer cells. Loss of phosphatase and tensin homologue deleted from chromosome 10 (PTEN) expression might acceler...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Kohnoh, Takashi, Hashimoto, Naozumi, Ando, Akira, Sakamoto, Koji, Miyazaki, Shinichi, Aoyama, Daisuke, Kusunose, Masaaki, Kimura, Motohiro, Omote, Norihito, Imaizumi, Kazuyoshi, Kawabe, Tsutomu, Hasegawa, Yoshinori
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Primary Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836157/
https://ncbi.nlm.nih.gov/pubmed/27095949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-016-0308-3
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