Repressive role of stabilized hypoxia inducible factor 1α expression on transforming growth factor β‐induced extracellular matrix production in lung cancer cells

Activation of transforming growth factor β (TGF‐β) combined with persistent hypoxia often affects the tumor microenvironment. Disruption of cadherin/catenin complexes induced by these stimulations yields aberrant extracellular matrix (ECM) production, characteristics of epithelial‐mesenchymal transi...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Ando, Akira, Hashimoto, Naozumi, Sakamoto, Koji, Omote, Norihito, Miyazaki, Shinichi, Nakahara, Yoshio, Imaizumi, Kazuyoshi, Kawabe, Tsutomu, Hasegawa, Yoshinori
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6549927/
https://ncbi.nlm.nih.gov/pubmed/31004547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14027
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