Direct regulation of transforming growth factor β‐induced epithelial–mesenchymal transition by the protein phosphatase activity of unphosphorylated PTEN in lung cancer cells

Transforming growth factor β (TGFβ) causes the acquisition of epithelial–mesenchymal transition (EMT). Although the tumor suppressor gene PTEN (phosphatase and tensin homologue deleted from chromosome 10) can negatively regulate many signaling pathways activated by TGFβ, hyperactivation of these sig...

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Bibliografiska uppgifter
I publikationen:Cancer Sci
Huvudupphovsmän: Kusunose, Masaaki, Hashimoto, Naozumi, Kimura, Motohiro, Ogata, Ryo, Aoyama, Daisuke, Sakamoto, Koji, Miyazaki, Shinichi, Ando, Akira, Omote, Norihito, Imaizumi, Kazuyoshi, Kawabe, Tsutomu, Hasegawa, Yoshinori
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2015
Ämnen:
Original Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714667/
https://ncbi.nlm.nih.gov/pubmed/26450531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12831
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