Direct regulation of transforming growth factor β‐induced epithelial–mesenchymal transition by the protein phosphatase activity of unphosphorylated PTEN in lung cancer cells

Transforming growth factor β (TGFβ) causes the acquisition of epithelial–mesenchymal transition (EMT). Although the tumor suppressor gene PTEN (phosphatase and tensin homologue deleted from chromosome 10) can negatively regulate many signaling pathways activated by TGFβ, hyperactivation of these sig...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Sci
Main Authors: Kusunose, Masaaki, Hashimoto, Naozumi, Kimura, Motohiro, Ogata, Ryo, Aoyama, Daisuke, Sakamoto, Koji, Miyazaki, Shinichi, Ando, Akira, Omote, Norihito, Imaizumi, Kazuyoshi, Kawabe, Tsutomu, Hasegawa, Yoshinori
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714667/
https://ncbi.nlm.nih.gov/pubmed/26450531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12831
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