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Structural analysis of a carcinogen-induced genomic rearrangement event.

We have explored the mechanism of genomic rearrangement in a hamster fibroblast cell culture system in which rearrangements are induced 5' to the endogenous thymidine kinase gene by chemical carcinogen treatment. The wild-type region around one rearrangement breakpoint was cloned and sequenced. With...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Barr, F G, Davis, R J, Eichenfield, L, Emanuel, B S
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1992
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48361/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1736310/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.3.942
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