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Thymidine-induced mutations in mammalian cells: sequence specificity and implications for mutagenesis in vivo.

Imbalances in the intracellular nucleotide precursor pools in mammalian cells can result in the induction of mutations during the DNA replication process. By using a shuttle vector system developed in our laboratory, we have analyzed the sequence specificity of mutations induced in mouse A9 cells by...

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Detalhes bibliográficos
Main Authors: Kresnak, M T, Davidson, R L
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC48756/
https://ncbi.nlm.nih.gov/pubmed/1557389
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