DNA adduct-induced stabilization of slipped frameshift intermediates within repetitive sequences: implications for mutagenesis.

Chemical carcinogens such as the aromatic amide 2-acetylaminofluorene (AAF) are known to induce -1 frameshift mutation hotspots at repetitive sequences. This mutagenesis pathway was suggested to involve slipped intermediates formed during replication. To investigate the stability and structure of su...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Garcia, A, Lambert, I B, Fuchs, R P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46852/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8327472/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.13.5989
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!