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Structural analysis of a carcinogen-induced genomic rearrangement event.

We have explored the mechanism of genomic rearrangement in a hamster fibroblast cell culture system in which rearrangements are induced 5' to the endogenous thymidine kinase gene by chemical carcinogen treatment. The wild-type region around one rearrangement breakpoint was cloned and sequenced....

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Autors principals: Barr, F G, Davis, R J, Eichenfield, L, Emanuel, B S
Format: Artigo
Idioma:Inglês
Publicat: 1992
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC48361/
https://ncbi.nlm.nih.gov/pubmed/1736310
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