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CD4 binding site broadly neutralizing antibody selection of HIV-1 escape mutants

All human immunodeficiency virus type-1 (HIV-1) viruses use CD4 to enter cells. Consequently, the viral envelope CD4-binding site (CD4bs) is relatively conserved, making it a logical neutralizing antibody target. It is important to understand how CD4-binding site variation allows for escape from neu...

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Bibliografski detalji
Izdano u:J Gen Virol
Glavni autori: Dreja, Hanna, Pade, Corinna, Chen, Lei, McKnight, Áine
Format: Artigo
Jezik:Inglês
Izdano: Society for General Microbiology 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835949/
https://ncbi.nlm.nih.gov/pubmed/25762593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.000120
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