Neuroinflammation increases GABAergic tone and impairs cognitive and motor function in hyperammonemia by increasing GAT-3 membrane expression. Reversal by sulforaphane by promoting M2 polarization of microglia

Lignende værker

• Hyperammonemia induces glial activation, neuroinflammation and alters neurotransmitter receptors in hippocampus, impairing spatial learning: reversal by sulforaphane
  af: Hernández-Rabaza, Vicente, et al.
  Udgivet: (2016)
• Sildenafil reduces neuroinflammation in cerebellum, restores GABAergic tone, and improves motor in‐coordination in rats with hepatic encephalopathy
  af: Agusti, Ana, et al.
  Udgivet: (2017)
• Infliximab reduces peripheral inflammation, neuroinflammation, and extracellular GABA in the cerebellum and improves learning and motor coordination in rats with hepatic encephalopathy
  af: Dadsetan, Sherry, et al.
  Udgivet: (2016)
• Sildenafil reduces neuroinflammation and restores spatial learning in rats with hepatic encephalopathy: underlying mechanisms
  af: Hernandez-Rabaza, Vicente, et al.
  Udgivet: (2015)
• Reducing Peripheral Inflammation with Infliximab Reduces Neuroinflammation and Improves Cognition in Rats with Hepatic Encephalopathy
  af: Dadsetan, Sherry, et al.
  Udgivet: (2016)