Prostacyclin-producing human mesenchymal cells target H19 lncRNA to augment endogenous progenitor function in hindlimb ischaemia

Promoting the paracrine effects of human mesenchymal stem cell (hMSC) therapy may contribute to improvements in patient outcomes. Here we develop an innovative strategy to enhance the paracrine effects of hMSCs. In a mouse hindlimb ischaemia model, we examine the effects of hMSCs in which a novel tr...

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Gepubliceerd in:Nat Commun
Hoofdauteurs: Deng, Yuxiao, Yang, Zhongwei, Terry, Toya, Pan, Su, Woodside, Darren G., Wang, Jingxiong, Ruan, Kehe, Willerson, James T., Dixon, Richard A. F., Liu, Qi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835554/
https://ncbi.nlm.nih.gov/pubmed/27080438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11276
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