Engineered Endothelial Progenitor Cells That Overexpress Prostacyclin Protect Vascular Cells

Prostacyclin (PGI2) is a potent vasodilator and important mediator of vascular homeostasis; however, its clinical use is limited because of its short (<2 minute) half-life. Thus, we hypothesize that the use of engineered endothelial progenitor cells (EPCs) that constitutively secrete high levels...

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Main Authors: Liu, Qi, Xi, Yutao, Terry, Toya, So, Shui-Ping, Mohite, Anita, Zhang, Jia, Wu, Geru, Liu, Xiaobing, Cheng, Jie, Ruan, Ke-He, Willerson, James T., Dixon, Richard A.F.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3292628/
https://ncbi.nlm.nih.gov/pubmed/21938725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.23035
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