Prostacyclin-producing human mesenchymal cells target H19 lncRNA to augment endogenous progenitor function in hindlimb ischaemia

Promoting the paracrine effects of human mesenchymal stem cell (hMSC) therapy may contribute to improvements in patient outcomes. Here we develop an innovative strategy to enhance the paracrine effects of hMSCs. In a mouse hindlimb ischaemia model, we examine the effects of hMSCs in which a novel tr...

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Publicado no:Nat Commun
Main Authors: Deng, Yuxiao, Yang, Zhongwei, Terry, Toya, Pan, Su, Woodside, Darren G., Wang, Jingxiong, Ruan, Kehe, Willerson, James T., Dixon, Richard A. F., Liu, Qi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835554/
https://ncbi.nlm.nih.gov/pubmed/27080438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11276
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