Prostacyclin-producing human mesenchymal cells target H19 lncRNA to augment endogenous progenitor function in hindlimb ischaemia

Promoting the paracrine effects of human mesenchymal stem cell (hMSC) therapy may contribute to improvements in patient outcomes. Here we develop an innovative strategy to enhance the paracrine effects of hMSCs. In a mouse hindlimb ischaemia model, we examine the effects of hMSCs in which a novel tr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Deng, Yuxiao, Yang, Zhongwei, Terry, Toya, Pan, Su, Woodside, Darren G., Wang, Jingxiong, Ruan, Kehe, Willerson, James T., Dixon, Richard A. F., Liu, Qi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835554/
https://ncbi.nlm.nih.gov/pubmed/27080438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11276
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