MIR517C inhibits autophagy and the epithelial-to-mesenchymal (-like) transition phenotype in human glioblastoma through KPNA2-dependent disruption of TP53 nuclear translocation

The epithelial-to-mesenchymal (-like) transition (EMT), a crucial embryonic development program, has been linked to the regulation of glioblastoma (GBM) progression and invasion. Here, we investigated the role of MIR517C/miR-517c, which belongs to the C19MC microRNA cluster identified in our prelimi...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Lu, Yuntao, Xiao, Limin, Liu, Yawei, Wang, Hai, Li, Hong, Zhou, Qiang, Pan, Jun, Lei, Bingxi, Huang, Annie, Qi, Songtao
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Basic Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4835194/
https://ncbi.nlm.nih.gov/pubmed/26553592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2015.1108507
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