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Deubiquitinases (DUBs) and DUB inhibitors: a patent review
INTRODUCTION: Deubiquitinating-enzymes (DUBs) are key components of the ubiquitin-proteasome-system (UPS). The fundamental role of DUBs is specific removal of ubiquitin from substrates. DUBs contribute to activation/deactivation, recycling and localization of numerous regulatory-proteins, thus playi...
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| Publicado en: | Expert Opin Ther Pat |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4834700/ https://ncbi.nlm.nih.gov/pubmed/26077642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543776.2015.1056737 |
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