Inhibition of 19S proteasome-associated deubiquitinases by metal-containing compounds

Copper and gold complexes have clinical activity in several diseases including cancer. Recently, we have reported that the anti-cancer activity of copper (II) pyrithione CuPT and gold (I) complex auranofin is associated with targeting the 19S proteasome-associated deubiquitinases (DUBs), UCHL5 and U...

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Bibliographic Details
Published in:Oncoscience
Main Authors: Liu, Ningning, Huang, Hongbiao, Ping Dou, Q., Liu, Jinbao
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468331/
https://ncbi.nlm.nih.gov/pubmed/26097878
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