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Metal-based proteasomal deubiquitinase inhibitors as potential anticancer agents

Deubiquitinases (DUBs) play an important role in protein quality control in eukaryotic cells due to their ability to specifically remove ubiquitin from substrate proteins. Therefore, recent findings have focused on the relevance of DUBs to cancer development, and pharmacological intervention on thes...

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Uloženo v:
Podrobná bibliografie
Vydáno v:Cancer Metastasis Rev
Hlavní autoři: Chen, Xin, Yang, Qianqian, Xiao, Lu, Tang, Daolin, Dou, Q. Ping, Liu, Jinbao
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721122/
https://ncbi.nlm.nih.gov/pubmed/29039082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-017-9701-1
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