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Metal-based proteasomal deubiquitinase inhibitors as potential anticancer agents

Deubiquitinases (DUBs) play an important role in protein quality control in eukaryotic cells due to their ability to specifically remove ubiquitin from substrate proteins. Therefore, recent findings have focused on the relevance of DUBs to cancer development, and pharmacological intervention on thes...

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Bibliografische gegevens
Gepubliceerd in:Cancer Metastasis Rev
Hoofdauteurs: Chen, Xin, Yang, Qianqian, Xiao, Lu, Tang, Daolin, Dou, Q. Ping, Liu, Jinbao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5721122/
https://ncbi.nlm.nih.gov/pubmed/29039082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-017-9701-1
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