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RAS signalling through PI3-Kinase controls cell migration via modulation of Reelin expression
RAS signalling through phosphoinositide 3-kinase (PI3-Kinase) has been shown to have an essential role in tumour initiation and maintenance. RAS also regulates cell motility and tumour invasiveness, but the role of direct RAS binding to PI3-Kinase in this remains uncertain. Here, we provide evidence...
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Publicado no: | Nat Commun |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4833863/ https://ncbi.nlm.nih.gov/pubmed/27071537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11245 |
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