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RAS Interaction with PI3K: More Than Just Another Effector Pathway

RAS proteins are small GTPases known for their involvement in oncogenesis: around 25% of human tumors present mutations in a member of this family. RAS operates in a complex signaling network with multiple activators and effectors, which allows them to regulate many cellular functions such as cell p...

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Detalhes bibliográficos
Main Authors: Castellano, Esther, Downward, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3128635/
https://ncbi.nlm.nih.gov/pubmed/21779497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911408079
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