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RAS Interaction with PI3K: More Than Just Another Effector Pathway
RAS proteins are small GTPases known for their involvement in oncogenesis: around 25% of human tumors present mutations in a member of this family. RAS operates in a complex signaling network with multiple activators and effectors, which allows them to regulate many cellular functions such as cell p...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
SAGE Publications
2011
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128635/ https://ncbi.nlm.nih.gov/pubmed/21779497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911408079 |
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