LRRC31 is induced by IL-13 and regulates kallikrein expression and barrier function in the esophageal epithelium

Eosinophilic esophagitis (EoE) is an allergic inflammatory disease of the esophagus featuring increased esophageal interleukin 13 (IL-13) levels and impaired barrier function. Herein, we investigated leucine-rich repeat–containing protein 31 (LRRC31) in human EoE esophageal tissue and IL-13–treated...

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發表在:Mucosal Immunol
Main Authors: D’Mello, RJ, Caldwell, JM, Azouz, NP, Wen, T, Sherrill, JD, Hogan, SP, Rothenberg, ME
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833724/
https://ncbi.nlm.nih.gov/pubmed/26462420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.98
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