17β-Estradiol protects the esophageal epithelium from IL-13–induced barrier dysfunction and remodeling

BACKGROUND: The incidence of eosinophilic esophagitis (EoE) is greater in male than female subjects, and the underlying molecular basis for this sex bias remains unclear. OBJECTIVE: We sought to delineate the contribution of the sex hormone estrogen to the EoE phenotype and esophageal epithelial bar...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Wheeler, Justin C., Vanoni, Simone, Zeng, Chang, Waggoner, Lisa, Yang, Yanfen, Wu, David, Uddin, Jazib, Karns, Rebekah, Kottyan, Leah, Mukkada, Vincent, Rothenberg, Marc E., Hogan, Simon P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6556402/
https://ncbi.nlm.nih.gov/pubmed/30578870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2018.10.070
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