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Identification of anoctamin 1 (ANO1) as a key driver of esophageal epithelial proliferation in eosinophilic esophagitis

BACKGROUND: The pathology of eosinophilic esophagitis (EoE) is characterized by eosinophil-rich inflammation, basal zone hyperplasia (BZH), and dilated intercellular spaces, and the underlying processes that drive the pathologic manifestations of the disease remain largely unexplored. OBJECTIVE: We...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Vanoni, Simone, Zeng, Chang, Marella, Sahiti, Uddin, Jazib, Wu, David, Arora, Kavisha, Ptaschinski, Catherine, Que, Jianwen, Noah, Taeko, Waggoner, Lisa, Barski, Artem, Kartashov, Andrey, Rochman, Mark, Wen, Ting, Martin, Lisa, Spence, Jason, Collins, Margaret, Mukkada, Vincent, Putnam, Phillip, Naren, Anjaparavanda, Chehade, Mirna, Rothenberg, Marc E., Hogan, Simon P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366251/
https://ncbi.nlm.nih.gov/pubmed/31647967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2019.07.049
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