Broad Transcriptional Response of the Human Esophageal Epithelium to Proton Pump Inhibitors

BACKGROUND: Proton pump inhibitors (PPIs) have been recognized as a primary treatment of eosinophilic esophagitis (EoE), an allergic inflammatory disease of the esophageal mucosa. The mechanisms underlying esophageal epithelial responses to PPIs remain poorly understood. OBJECTIVE: We hypothesized t...

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Bibliographic Details
Published in:J Allergy Clin Immunol
Main Authors: Rochman, M., Xie, Y-M., Mack, L., Caldwell, J.M, Klingler, A.M., Osswald, G.A., Azouz, N.P., Rothenberg, M.E.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8062577/
https://ncbi.nlm.nih.gov/pubmed/33289661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2020.09.039
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