Effects of Combined Treatment With Arsenic Trioxide and Itraconazole in Patients With Refractory Metastatic Basal Cell Carcinoma

IMPORTANCE: Tumor resistance is an emerging problem for Smoothened (SMO) inhibitor–treated metastatic basal cell carcinoma (BCC). Arsenic trioxide and itraconazole antagonize the hedgehog (HH) pathway at sites distinct from those treated by SMO inhibitors. OBJECTIVE: To determine whether administrat...

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Bibliografski detalji
Izdano u:JAMA Dermatol
Glavni autori: Ally, Mina S., Ransohoff, Katherine, Sarin, Kavita, Atwood, Scott X., Rezaee, Melika, Bailey-Healy, Irene, Kim, Jynho, Beachy, Philip A., Chang, Anne Lynn S., Oro, Anthony, Tang, Jean Y., Colevas, A. Dimitrios
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833646/
https://ncbi.nlm.nih.gov/pubmed/26765315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamadermatol.2015.5473
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