Effects of Combined Treatment With Arsenic Trioxide and Itraconazole in Patients With Refractory Metastatic Basal Cell Carcinoma

IMPORTANCE: Tumor resistance is an emerging problem for Smoothened (SMO) inhibitor–treated metastatic basal cell carcinoma (BCC). Arsenic trioxide and itraconazole antagonize the hedgehog (HH) pathway at sites distinct from those treated by SMO inhibitors. OBJECTIVE: To determine whether administrat...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:JAMA Dermatol
Autores principales: Ally, Mina S., Ransohoff, Katherine, Sarin, Kavita, Atwood, Scott X., Rezaee, Melika, Bailey-Healy, Irene, Kim, Jynho, Beachy, Philip A., Chang, Anne Lynn S., Oro, Anthony, Tang, Jean Y., Colevas, A. Dimitrios
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833646/
https://ncbi.nlm.nih.gov/pubmed/26765315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamadermatol.2015.5473
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares