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Nineteen-Step Total Synthesis of (+)-Phorbol
Phorbol, the flagship member of the tigliane diterpene family, has been known for over 80 years and has attracted attention from scores of chemists and biologists due to its intriguing chemical structure and the medicinal potential of phorbol esters.(1) Access to useful quantities of phorbol and rel...
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| Veröffentlicht in: | Nature |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4833603/ https://ncbi.nlm.nih.gov/pubmed/27007853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17153 |
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