Genome-Wide CRISPR-Cas9 Screen Identifies MicroRNAs That Regulate Myeloid Leukemia Cell Growth

Mammalian microRNA expression is dysregulated in human cancer. However, the functional relevance of many microRNAs in the context of tumor biology remains unclear. Using CRISPR-Cas9 technology, we performed a global loss-of-function screen to simultaneously test the functions of individual microRNAs...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Wallace, Jared, Hu, Ruozhen, Mosbruger, Timothy L., Dahlem, Timothy J., Stephens, W. Zac, Rao, Dinesh S., Round, June L., O’Connell, Ryan M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833428/
https://ncbi.nlm.nih.gov/pubmed/27081855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153689
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker