Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

MicroRNAs regulate gene expression posttranscriptionally and function within the cells in which they are transcribed. However, recent evidence suggests that microRNAs can be transferred between cells and mediate target gene repression. We find that endogenous miR-155 and miR-146a, two critical micro...

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Pubblicato in:Nat Commun
Autori principali: Alexander, Margaret, Hu, Ruozhen, Runtsch, Marah C., Kagele, Dominique A., Mosbruger, Timothy L., Tolmachova, Tanya, Seabra, Miguel C., Round, June L., Ward, Diane M., O'Connell, Ryan M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Pub. Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557301/
https://ncbi.nlm.nih.gov/pubmed/26084661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8321
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