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Exosome-delivered microRNAs modulate the inflammatory response to endotoxin

MicroRNAs regulate gene expression posttranscriptionally and function within the cells in which they are transcribed. However, recent evidence suggests that microRNAs can be transferred between cells and mediate target gene repression. We find that endogenous miR-155 and miR-146a, two critical micro...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Alexander, Margaret, Hu, Ruozhen, Runtsch, Marah C., Kagele, Dominique A., Mosbruger, Timothy L., Tolmachova, Tanya, Seabra, Miguel C., Round, June L., Ward, Diane M., O'Connell, Ryan M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Pub. Group 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4557301/
https://ncbi.nlm.nih.gov/pubmed/26084661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8321
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