Rab27-dependent exosome production inhibits chronic inflammation and enables acute responses to inflammatory stimuli

Extracellular vesicles, including exosomes, have recently been implicated as novel mediators of immune cell communication in mammals. However, roles for endogenously produced exosomes in regulating immune cell functions in vivo are just beginning to be identified. Here, we demonstrate that Rab27a an...

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Vydáno v:J Immunol
Hlavní autoři: Alexander, Margaret, Ramstead, Andrew G., Bauer, Kaylyn M., Lee, Soh-Hyun, Runtsch, Marah C., Wallace, Jared, Huffaker, Thomas B., Larsen, Dane K., Tolmachova, Tanya, Seabra, Miguel C., Round, June L., Ward, Diane M., O’Connell, Ryan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5821227/
https://ncbi.nlm.nih.gov/pubmed/28978688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700904
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