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One Year of Enzyme Replacement Therapy Reduces Globotriaosylceramide Inclusions in Podocytes in Male Adult Patients with Fabry Disease

Fabry nephropathy is associated with progressive accumulation of globotriaosylceramide (GL3) in podocytes. Reducing this GL3 burden may reduce podocyte injury. Sensitive methods to quantify podocyte GL3 content may determine whether a given strategy can benefit podocytes in Fabry disease. We develop...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Najafian, Behzad, Tøndel, Camilla, Svarstad, Einar, Sokolovkiy, Alexey, Smith, Kelly, Mauer, Michael
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833322/
https://ncbi.nlm.nih.gov/pubmed/27081853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152812
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