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One Year of Enzyme Replacement Therapy Reduces Globotriaosylceramide Inclusions in Podocytes in Male Adult Patients with Fabry Disease

Fabry nephropathy is associated with progressive accumulation of globotriaosylceramide (GL3) in podocytes. Reducing this GL3 burden may reduce podocyte injury. Sensitive methods to quantify podocyte GL3 content may determine whether a given strategy can benefit podocytes in Fabry disease. We develop...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Najafian, Behzad, Tøndel, Camilla, Svarstad, Einar, Sokolovkiy, Alexey, Smith, Kelly, Mauer, Michael
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833322/
https://ncbi.nlm.nih.gov/pubmed/27081853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152812
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