One Year of Enzyme Replacement Therapy Reduces Globotriaosylceramide Inclusions in Podocytes in Male Adult Patients with Fabry Disease

Fabry nephropathy is associated with progressive accumulation of globotriaosylceramide (GL3) in podocytes. Reducing this GL3 burden may reduce podocyte injury. Sensitive methods to quantify podocyte GL3 content may determine whether a given strategy can benefit podocytes in Fabry disease. We develop...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Najafian, Behzad, Tøndel, Camilla, Svarstad, Einar, Sokolovkiy, Alexey, Smith, Kelly, Mauer, Michael
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4833322/
https://ncbi.nlm.nih.gov/pubmed/27081853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152812
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