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Predicting allopurinol response in patients with gout
AIMS: The primary aim of this research was to predict the allopurinol maintenance doses required to achieve the target plasma urate of ≤0.36 mmol l(−1). METHODS: A population analysis was conducted in nonmem using oxypurinol and urate plasma concentrations from 133 gout patients. Maintenance dose pr...
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| Pubblicato in: | Br J Clin Pharmacol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4833152/ https://ncbi.nlm.nih.gov/pubmed/26451524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12799 |
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