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Predicting allopurinol response in patients with gout
AIMS: The primary aim of this research was to predict the allopurinol maintenance doses required to achieve the target plasma urate of ≤0.36 mmol l(−1). METHODS: A population analysis was conducted in nonmem using oxypurinol and urate plasma concentrations from 133 gout patients. Maintenance dose pr...
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Publicado no: | Br J Clin Pharmacol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
John Wiley and Sons Inc.
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4833152/ https://ncbi.nlm.nih.gov/pubmed/26451524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12799 |
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